Nbs handbook 145, 1986, handbook for the quality assurance of metrological measurements, by john k. Snap the neck off an alkalinity ampule standard, 0. Classical benchtop ph meter is equipped with a backlit lcd display. Operation and calibration of ph meter pharma beginners. Procedures for chainofcustody, sop development, and. Quality assurancequality control engineering umass. However, if the ph of any industrial byproduct material e. This standard operating procedure is applicable for formulation plant of pharmaceutical company name with. Standard operating procedures analysis of ph this guidance document was prepared to assist research assistants, postdocs and lab technicians in conducting analysis of ph in the umass environmental. Standard operating procedure for calibration and maintenance of ph meters sop number.
Place aqueous samples, headspacefree in a refrigerator until analysis. The purpose of this sop standard operating procedure is to describe the procedure of operation, standardization, and maintenance of ph meter. The ph sop shall be updated whenever necessary to reflect any changes in the procedures used. The purpose of this standard operating procedure sop is to establish all the necessary steps to use, store, and care for a ph electrode. Record all the observation in ph calibration record.
Technical note ph calibration procedure for optimal. The measurement of dissolved oxygen, temperature, specific conductance, ph, and chloride using the ysi professional plus handheld multiparameter meter. This may be done by turning a small screw on the conductivity meter. The custom liquid crystal display simultaneously shows temperature compensated ph. Report sop ph meter please fill this form, we will try to respond as soon as possible. This article provides a detailed description of the usp 791 requirements for ph measurements. Standard operating procedure measurement of ph chemsop 1.
Laboratory determination of soil ph by aqueous solution. This document is the standard operating procedure sop for conducting field measurements of ph, conductivity, and temperature using a handheld multiparameter meter and sensor. Take out the sample and switch off lamp and moisture meter. Sop for calibration of ph meter and product ph measurement calibration of ph meter sausage maker or designee will calibrate the ph meter prior to use. Masswwp standard operating procedure r4 ph and alkalinity. Maintenance and calibration of ph meter document no. Use the procedures recommended by manufacturer of equipment this will vary, but a general version is shown below.
Missouri state university and ozarks environmental and. Purpose to outline the procedure for operation of typical ph meter in the traces centre and the undergraduate laboratories. Oppermann is out of print and the majority of content has been updated and. Sop on operation and calibration of ph meter a blog about pharmaceutical quality control, quality assurance, microbiology, production and regulatory updates provided by. Standard operating procedure sop for operation, standardization, calibration, and maintenance of ph meter including ph meter electrode care. When the ph meter is in use for longer than 3 hours, the ph of the third buffer shall be. When analyzing wastes or samples with extreme higher or lower ph, use a more appropriate buffer closer to the expected ph range. Additionally, sops for other meters that measure these parameters are included.
Omcl network of the council of europe quality management document pa ph omcl 86 3r. Speci c attention is given to address the di erences in measuring solid and liquid samples. It also contains guidance on the instrumentation specifications and usage, as well as tips and tricks on how. Standard operating procedure for calibration of field instruments temperature, ph, dissolved oxygen, conductivityspecific conductance, oxidationreduction potential, and turbidity pdf. Standard operating procedure for electrometric ph 1.
Check the conductivity meter reading against the value obtained in step 2. The combination electrode is relatively free from interference from color, turbidity, colloidal matter. Next, put a clean electrode in the neutral buffer and press the measure or calibrate button. In this method, a calibrated ph meter is used to measure the ph value for water samples in the laboratory. Model 350 ph meter operating instructions introduction the model 350 is a general purpose hand held ph meter offering a 1 or 2 point calibration and automatic buffer recognition with manual override. Glp sops for equipment calibration and maintenance. Natural waters generally have a ph value between 4 and 9 standard methods, 2005. Scope this standard operating procedure sop applies to the staff and students using the hanna benchtop ph meter hi 8521 in the laboratories of the pharmacy department, university of malta. Signup for the free email updates for your daily dose of pharmaceutical tipsmoc. A blog about pharmaceutical quality control, quality assurance, microbiology, production and regulatory updates provided by regulatory agencies. Sop on operation and calibration of ph meter a blog about pharmaceutical quality control, quality assurance, microbiology, production and regulatory updates provided by regulatory agencies. Adjust the conductivity meter if possible and needed.
Once you have a stable reading, set the ph meter to the buffers ph. This procedure describes how to accurately measure the ph of a solution. Sop templates and sop on sops irina colligon1, and michelle rosa2 1downingtown, pa, usa 2bethlehem, pa, usa summary document. To lay down procedure for calibration and operation of ph meter. For greatest accuracy, it is recommended that the instrument be calibrated. Standard operating procedure ambl205b laboratory determination of soil ph by aqueous solution extraction. These are the official versions cited in the dep qa rule, chapter 62160, f. Automatic electrode diagnosis helps the user decide whether to replace the ph.
To calibrate and use a ph meter, prepare a neutral buffer with a ph of 7 and a second buffer with a ph of 4 for acidic samples or 9. Standard operating procedure for ozarks environmental and. Note down the weight and moisture percentage as indicated in graduated scale. Other buffers may be used to achieve desired range of measurement. Procedures for chainofcustody, sop development, and common field parameter measurements do, ph, chlorine, temperature office of environmental laboratory. Thermo scientific ph meters contain ph versus temperature. Ketika angka ph yang ditampilkan sudah stabil dan tulisan ready muncul, tekan tombol enter untuk menyimpan hasil kalibrasi buffer ph. Sop for calibration of ph meter and product ph measurement. Measurement of soil ph using a potentiometer determines the degree of acidity.
Standard operating procedure for electrometric ph cromlab. The ph meter objective to describe the procedure for operation of ph meter scope this sop is applicable for the operation of ph meter. Perform a calibration verification on at least one other ph. Dep sops florida department of environmental protection. Sop 52 verification and adjustment of digital conductivity. Gloves and protective eyewear should be worn when handling samples and reagents buffers, however it is preferable that the user. The glass electrode is relatively free from interference from color, turbidity.
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